Reimagining Neuromodulation for
Cardiac Rhythm Care
StimCardio Medical is developing a non-invasive, wearable neuromodulation platform that integrates continuous physiological sensing with personalized therapy, designed for use in everyday life, beginning with atrial fibrillation.
Disclaimer: StimCardio’s technology is considered investigational and is not yet approved for commercial use.
Atrial Fibrillation by the Numbers
52.5M+
People
worldwide
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~5×
Increased risk of ischemic stroke
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1 in 3-5
Lifetime risk
after age 40
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>60%
AF recurrence within
one year
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$36B
Annual healthcare
cost in the U.S.
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~500K AF
Related hospitalizations each year
52.5M+
People
worldwide
~5×
Increased risk of ischemic stroke
1 in 3-5
Lifetime risk
after age 40
>60%
AF recurrence within
one year
$36B
Annual healthcare
cost in the U.S.
~500K AF
Related hospitalizations each year
Personalized Neuromodulation Designed Around the Patient
StimCardio’s integrated platform continuously monitors patients, analyzes physiological signals, and delivers personalized peripheral neuromodulation to restore autonomic balance and reduce atrial fibrillation.
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Personalized neuromodulation
informed by individual rhythm patterns
Continuous sensing
of cardiac and autonomic signals from optical and electrical (EKG) signals
Cloud-based analysis
of physiological data
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Cloud-based analysis
of physiological data
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Continuous sensing
of cardiac and autonomic signals from optical and electrical (EKG) signals
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Personalized neuromodulation
informed by individual rhythm patterns
Using real-time cardiac and autonomic data, the system enables continuous arrhythmia detection and adaptive neuromodulation. By modulating peripheral pathways that influence the autonomic nervous system, the platform improves heart–brain communication and is designed to reduce atrial fibrillation burden over time.
Why Neuromodulation
Neuromodulation is a rapidly evolving new class of medical device therapy that targets neural pathways involved in cardiovascular regulation, offering a non-invasive way to engage systems that influence heart rhythm dynamics.
StimCardio’s approach focuses on:
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Peripheral nerve engagement through wrist-based stimulation
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Central autonomic modulation pathways
Integration of neuromodulation with real-time monitoring of physiological data
This system-level approach is designed to complement existing clinical strategies rather than replace them.
Continuous Engagement
in Everyday Settings
Sentio™ is a wrist-worn, non-invasive wearable that delivers personalized neuromodulation through a closed-loop approach.
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Built on Clinical Insight and Ongoing Research
StimCardio is conducting a multi-stage clinical program that includes feasibility studies, randomized pilot studies, mechanism-of-action investigations, and ongoing multicenter trials.
